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  1. Jason W Boland
  1. Senior Clinical Lecturer And Honorary Consultant In Palliative Medicine Hull York Medical School, University Of Hull, UK

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Predictors of anxiety and depression in people with colorectal cancer


Using questionnaires and clinical records, this study investigated anxiety and depression in people with colorectal cancer and identified factors associated with them. Nearly 500 people in Scotland with colorectal cancer between 2006 and 2008 completed the Hospital Anxiety and Depression Scale and information was collected on functioning, symptoms and social difficulties. Twenty per cent of participants had possible or probable anxiety and 17% had possible or probable depression, with nearly 50% of those with anxiety having coexisting depression. Anxiety levels were similar to non-clinical samples, but depression was higher. Self-reported history of anxiety or depression predicted anxiety but not depression. Self-reported anxiety and depression, dyspnoea, diarrhoea and poor cognitive function predicted anxiety. Having poor physical, cognitive and social functioning, having difficulties with personal care and communicating, being constipated or having neoadjuvant radiotherapy was associated with depression. As this group of people are at increased risk of depression, it is important to consider and optimise these modifiable factors which are associated with depression.

Complications and survival associated with operative procedures in patients with unresectable pancreatic head adenocarcinoma


In a retrospective chart review study, from 1997 to 2013 in a US hospital, 50 patients with adenocarcinoma of the pancreatic head who underwent surgical exploration with curative intent but who did not undergo pancreatectomy were evaluated (these account for about 20% of patients taken for resection). They were unresectable due to metastatic disease or due to vascular invasion. Sixty-eight per cent of these patients had …

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  • Competing interests None.

  • Provenance and peer review Commissioned; internally peer reviewed.