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Poster Numbers 1 to 29 – Palliative care: all conditions and all ages: Poster No: 25
The experiences of palliative lung cancer patients participating in a clinical trial
  1. Stephanie Sivell1,
  2. Simon Noble1,
  3. Emily Harrop1,
  4. Anthony Byrne1,
  5. Barbara Moore2 and
  6. Annmarie Nelson3
  1. 1Marie Curie Palliative Care Research Centre, WCTU, School of Medicine, Cardiff University, Wales, UK
  2. 2Cancer Research UK, NISCHR Cardiff, Wales, UK
  3. 3Marie Curie Palliative Care Research Centre, WCTU, School of Medicine, Cardiff University, Wales, UK


Background Palliative care lung cancer patients are under-represented in oncology trials and very little is understood about their experiences of participating in clinical trials. FRAGMATIC is the largest lung cancer study in the UK and is investigating the effects of Fragmin (a self-injected anticoagulant) in patients with lung cancer. This current study (QUALFRAG) is a qualitative substudy of the FRAGMATIC trial.

Aims To explore patients' experiences of participating in FRAGMATIC and the impact on quality of life, while at the same time collecting data on patients' experiences of advanced lung cancer.

Methods Semistructured interviews will be held with two groups of 6–10 patients (12–20 patients in total) recruited from the intervention and control arms of the FRAGMATIC trial.

Analysis Interviews will be analysed using Interpretative Phenomenological Analysis (IPA) to identify emergent themes that reflect participants' lived experience.

Results Data will be presented on patients' experiences of participating in the FRAGMATIC study, symptom progression and (where relevant) how tolerable Fragmin is.

Conclusions The results of this study will help future studies target appropriate symptom control issues in palliative lung cancer patients and inform future healthcare management with respect to the treatment and prevention of cancer associated thrombosis.

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