Multicentre, double-blind, randomised placebo-controlled clinical trial on the efficacy of methylphenidate on depressive symptoms in advanced cancer patients

Carlos Centeno; Alvaro Sanz; Miguel Angel Cuervo; Daniel Ramos; Silvia Hernansanz; Jesús Gonzalez; Maria Jose Almaraz; Marcos Lama; Francisco Vara; María Nabal; Antonio Pascual

doi:10.1136/bmjspcare-2011-000093

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Multicentre, double-blind, randomised placebo-controlled clinical trial on the efficacy of methylphenidate on depressive symptoms in advanced cancer patients

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	Abstract	Full	Pdf
Jun 2012	192	4	6
Jul 2012	98	2	5
Aug 2012	55	4	1
Sep 2012	99	2	4
Oct 2012	106	5	0
Nov 2012	198	4	17
Dec 2012	227	5	11
Jan 2013	269	6	16
Feb 2013	171	2	9
Mar 2013	155	2	12
Apr 2013	117	1	5
May 2013	158	1	2
Jun 2013	54	1	3
Jul 2013	57	1	2
Aug 2013	36	0	2
Sep 2013	55	0	3
Oct 2013	51	2	4
Nov 2013	85	5	7
Dec 2013	70	4	10
Jan 2014	61	5	17
Feb 2014	50	5	2
Mar 2014	62	10	7
Apr 2014	91	26	17
May 2014	90	12	16
Jun 2014	51	7	5
Jul 2014	40	14	7
Aug 2014	55	10	4
Sep 2014	32	14	16
Oct 2014	63	28	7
Nov 2014	51	14	8
Dec 2014	43	9	6
Jan 2015	46	6	11
Feb 2015	23	0	1
Mar 2015	69	3	1
Apr 2015	34	3	3
May 2015	23	1	0
Jun 2015	35	1	1
Jul 2015	28	1	2
Aug 2015	16	0	1
Sep 2015	22	1	2
Oct 2015	16	0	2
Nov 2015	31	0	1
Dec 2015	19	2	3
Jan 2016	28	2	4
Feb 2016	23	0	0
Mar 2016	13	0	2
Apr 2016	19	2	2
May 2016	25	2	3
Jun 2016	15	0	0
Jul 2016	13	2	1
Aug 2016	20	1	0
Sep 2016	20	1	1
Oct 2016	26	0	0
Nov 2016	43	7	1
Dec 2016	24	0	0
Jan 2017	22	0	1
Feb 2017	28	0	0
Mar 2017	21	3	1
Apr 2017	18	5	4
May 2017	31	0	0
Jun 2017	12	1	1
Jul 2017	52	2	3
Aug 2017	37	1	1
Sep 2017	55	1	1
Oct 2017	91	1	1
Nov 2017	57	1	0
Dec 2017	66	1	1
Jan 2018	73	1	1
Feb 2018	167	1	1
Mar 2018	164	7	1
Apr 2018	106	6	0
May 2018	110	0	0
Jun 2018	59	0	0
Jul 2018	38	0	0
Aug 2018	50	1	1
Sep 2018	19	0	0
Oct 2018	47	0	0
Nov 2018	73	0	0
Dec 2018	116	2	2
Jan 2019	69	0	0
Feb 2019	86	1	0
Mar 2019	35	0	0
Apr 2019	13	2	1
May 2019	14	1	0
Jun 2019	14	0	0
Jul 2019	28	2	0
Aug 2019	25	0	0
Sep 2019	48	1	1
Oct 2019	29	1	1
Nov 2019	8	0	4
Dec 2019	52	0	0
Jan 2020	34	0	1
Feb 2020	27	0	0
Mar 2020	34	1	1
Apr 2020	62	0	0
May 2020	57	1	0
Jun 2020	14	0	0
Jul 2020	29	1	1
Aug 2020	13	1	0
Sep 2020	57	2	0
Oct 2020	53	1	2
Nov 2020	48	0	1
Dec 2020	83	1	1
Jan 2021	154	0	0
Feb 2021	51	0	0
Mar 2021	101	1	3
Apr 2021	25	1	2
May 2021	21	2	1
Jul 2021	1	1	0
Aug 2021	1	1	1
Sep 2021	5	2	1
Oct 2021	147	3	0
Nov 2021	64	0	4
Dec 2021	31	0	0
Jan 2022	36	2	0
Feb 2022	29	0	0
Mar 2022	32	1	0
Apr 2022	69	0	0
May 2022	45	1	0
Jun 2022	77	11	2
Jul 2022	29	0	0
Aug 2022	78	1	1
Sep 2022	90	5	3
Oct 2022	258	7	5
Nov 2022	159	2	1
Dec 2022	99	1	2
Jan 2023	75	0	0
Feb 2023	86	0	0
Mar 2023	8	0	0
Apr 2023	25	1	1
May 2023	27	0	0
Jun 2023	43	0	0
Jul 2023	20	0	0
Aug 2023	43	0	0
Sep 2023	49	2	0
Oct 2023	17	3	0
Nov 2023	68	3	0
Dec 2023	77	7	1
Jan 2024	53	6	5
Feb 2024	67	0	2
Mar 2024	134	1	1
Total	8411	355	343

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