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Cancer pain management: long-term maintenance therapy
  1. Sebastiano Mercadante,
  2. Giuseppe Bellavia and
  3. Fausto Giuliana
  1. Pain Relief and Supportive Care, Private Hospital La Maddalena, Palermo, Italy
  1. Correspondence to Dr Sebastiano Mercadante, Pain Relief and Supportive Care, Private Hospital La Maddalena, Palermo 90146, Italy; terapiadeldolore{at}


This is a case report regarding a patient on maintenance therapy with methadone wth cancer pain. Minimal increase in methadone dose and a better modulation of administration intervals were effective, allowing the achievement of an optimal analgesia in a short time. This effect was maintained at home after discharge up the last follow-up 3 weeks after discharge. Existing literature is discussed and it is suggested to use the same drug, methadone, in increased doses.

  • Cancer
  • Pain
  • Head and neck
  • Hospital care
  • Supportive care
  • Drug administration

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  • Collaborators na.

  • Contributors All authors contributed equally to manage the case. SM wrote the article with approval of the other authors.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.