Background The survival of hospitalized cancer patients with pressure injury (PI) has not been studied in large cohort.

Objective To assess risk factors associated with the overall survival (OS) of hospitalized cancer patients with PI.

Methods After IRB approval, this retrospective study was conducted in tertiary cancer center in United States. Medical records from hospitalized patients referred to Wound Ostomy Continence Nurse for pressure injuries from August 2016 to August 2017 are reviewed. Kaplan-Meier method was used to estimate the OS time and log-rank test was used to assess the association between OS and other variables.

Results Among the 445 adult cancer patients with PI, the OS rate is 55.3% at 1 month. OS is significantly associated with Braden Scale (BS). The OS time is significantly shorter in patients with advanced disease (p<0.0001). In a multicovariate Cox model, adjusted for advanced disease (HR=4.33, p<.0001), BS ≥15 are significantly associated with longer OS time when compared to patients with BS ≤ 14 (HR=0.44, p<.0001; HR=0.47, p<.0001, respectively).

Conclusion Cancer patients with PI have limited OS, especially those with ≤ 14 BS and advanced diseases.