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Nasal fentanyl and buccal midazolam carer administration ‘as needed’ for breakthrough symptom control in a specialist palliative care unit: a nested qualitative study
  1. Paul Perkins1,2,
  2. Anne Parkinson1,
  3. Vanessa Taylor3 and
  4. Emma Husbands2
  1. 1 Leckhampton Court Hospice, Cheltenham, Gloucestershire, UK
  2. 2 Palliative Medicine, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, Gloucestershire, UK
  3. 3 Department of Nursing, Midwifery & Health, Northumbria University Faculty of Health and Life Sciences, Newcastle upon Tyne, UK
  1. Correspondence to Dr Paul Perkins, Leckhampton Court Hospice, Cheltenham GL53 0QJ, UK; paul.perkins{at}suerydercare.org

Abstract

Introduction When people are dying and unable to take oral medication, injectable medication is commonly used, usually administered by healthcare professionals. There may be delays to symptom relief due to travel to the person’s home. In a randomised controlled trial (RCT) previously reported, nasal fentanyl (NF) or buccal midazolam (BM) were administered by lay carers in a hospice.

Objective (1) To report experiences of lay carers who administered NF and BM for symptom control and (2) To use feedback to develop guidance informing a future definitive RCT to determine whether NF and BM administered by lay carers can lead to timely, improved symptom control for people dying at home and fewer ‘emergency’ community nursing visits than standard breakthrough medication administered by healthcare professionals.

Material and methods Semistructured interviews with lay carers who gave trial medication were conducted. Interview data were analysed using a stage by stage method to code and categorise transcripts.

Findings The six themes were: (1) Participation—lay carers welcomed the opportunity to administer medication; (2) Ease of use—lay carers found preparations easy to use; (3) How things could have been done differently—lay carers would have liked access to trial drugs at home; (4) Training—lay carers were happy with the training they received; (5) Timing—lay carers liked the immediacy of trial drugs and (6) Evaluation—assessing symptom intensity and drug efficacy.

Conclusions Participation was acceptable to patients and lay carers, and beneficial for symptom relief. The findings will inform planning for a future community-based study.

  • cancer
  • drug administration
  • home care
  • hospice care
  • symptoms and symptom management
  • terminal care

Data availability statement

Data are available on reasonable request. Unpublished data are held by Sue Ryder Leckhampton Court Hospice.

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Data availability statement

Data are available on reasonable request. Unpublished data are held by Sue Ryder Leckhampton Court Hospice.

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Footnotes

  • Twitter @mdoc77

  • Contributors PP conceived the study. AP and EH made substantial contribution to its design. AP and BD collected the data. AP and PP analysed the data. VT gave methodological advice. All authors critically revised drafts of the paper. They also read and approved the final version of the manuscript. PP is the guarantor.

  • Funding Kyowa Kirin provided PecFent supplies free of charge and lock boxes for the trial. Special Products provided Epistatus free of charge. Both companies provided funding to enable the study to be conducted.

  • Competing interests PP and EH have in the past received financial support to attend educational events from Kyowa Kirin. Neither drug company gave any input to this submission.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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