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Parecoxib for opioid-induced hyperalgesia
  1. Emily Kellett1,
  2. Richard Berman2,
  3. Helen Morgan3 and
  4. Joanne Collins4
  1. 1 Department of Palliative & Supportive Care, The Christie NHS Foundation Trust, Manchester, UK
  2. 2 Department of Supportive Care, Christie NHS Foundation Trust, Manchester, UK
  3. 3 Macmillan Consultant Palliative Medicine, Department of Supportive & Palliative Care, The Christie NHS Foundation Trust, Manchester, UK
  4. 4 Department of Pharmacy, The Christie NHS Foundation Trust, Manchester, UK
  1. Correspondence to Dr Emily Kellett, Department of Palliative & Supportive Care, The Christie NHS Foundation Trust, Manchester, UK; e.kellett1{at}nhs.net

Abstract

This paper describes the case report of a patient admitted to hospital with severe and complex pain and subacute bowel obstruction, who failed to respond to multiple analgesic regimens including ketamine burst and opioid rotation, and was subsequently successfully managed with a parecoxib infusion.

  • cancer
  • pain
  • supportive care
  • drug administration

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Footnotes

  • Twitter @bermandr2

  • Contributors Conception and design of article: EK, HM, RB. Drafting the manuscript: EK, HM. Revising the manuscript critically for important intellectual content: JC. Approval of the version of the manuscript to be published: EK, HM, RB, JC.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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