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Propofol for palliative sedation
  1. Merlina Sulistio1,2,
  2. Robert Wojnar1 and
  3. Natasha G Michael1,2,3
  1. 1 Department of Palliative and Supportive Care, Cabrini Health, Melbourne, Victoria, Australia
  2. 2 Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia
  3. 3 School of Medicine, University of Notre Dame, Sydney, New South Wales, Australia
  1. Correspondence to Dr Merlina Sulistio, Supportive and Palliative Care Unit, Cabrini Health, Prahran, VIC 3181, Australia; msulistio{at}


Palliative sedation is the intentional use of sedatives to manage refractory symptom(s), such as pain and/or terminal restlessness. This case report describes the successful use of propofol, an ultra-fast-acting anaesthetic agent commonly used for anaesthesia induction and maintenance to manage refractory agitated delirium in an acute inpatient palliative medicine setting.

  • propofol
  • sedative
  • sedation
  • palliative care
  • end of life care

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  • Contributors Background research by MS and RW. Article written by MS and RW with editorial input from NGM. Article submitted by MS. The guarantor for content is MS.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Next-of-kin consent obtained.

  • Provenance and peer review Not commissioned; internally peer reviewed.