• The instrument successfully differentiates between highand low-quality guideline content. 7•
The new user’s manual is well received by users. 7• Users provided considerable …

Background: Evidence-based clinical guidelines aim to improve the quality of care. In The
Netherlands, considerable time and effort have been invested in the development and …

Purpose. The development and updating of high-quality clinical practice guidelines require
substantial resources. Many guideline programmes throughout the world are using similar …

Background Despite wide distribution and promotion of clinical practice guidelines,
adherence among Dutch general practitioners (GPs) is not optimal. To improve adherence to …

Background: We established a program of research to improve the development, reporting
and evaluation of practice guidelines. We assessed the construct validity of the items and user…

Background: We undertook research to improve the AGREE instrument, a tool used to evaluate
guidelines. We tested a new seven-point scale, evaluated the usefulness of the original …

Objective. To describe systematically the structures and working methods of guideline programs.
Design. Descriptive survey using a questionnaire with 32 items based on a framework …

Background Despite considerable efforts to promote and support guideline use, adherence
is often suboptimal. Barriers to adherence vary not only across guidelines but also across …

BACKGROUND: The use of clinical guidelines in general practice is often limited. Research
on barriers to guideline adherence usually focuses on attitudinal factors. Factors linked to …

Background Guidelines traditionally focus on the diagnosis and treatment of single diseases.
As almost half of the patients with a chronic disease have more than one disease, the …