Abstract Objective The Surviving Sepsis Campaign (SSC or “the Campaign”) developed
guidelines for management of severe sepsis and septic shock. A performance improvement …

For more than two decades, sepsis was defined as a microbial infection that produces fever
(or hypothermia), tachycardia, tachypnoea and blood leukocyte changes. Sepsis is now …

Purpose To investigate the global burden of sepsis in hospitalized adults by updating and
expanding a systematic review and meta-analysis and to compare findings with recent …

Background Sepsis is life-threatening organ dysfunction due to a dysregulated host
response to infection. It is considered a major cause of health loss, but data for the global …

Background Hydrocortisone is widely used in patients with septic shock even though a
survival benefit has been reported only in patients who remained hypotensive after fluid and …

Background and study aims: Flat lesions pose new challenges for endoscopists, but the
importance of detecting them is still controversial. Most screening studies do not survey …

Rationale: Reducing the global burden of sepsis, a recognized global health challenge,
requires comprehensive data on the incidence and mortality on a global scale. Objectives …

Objective: To provide an update to the “Surviving Sepsis Campaign Guidelines for
Management of Severe Sepsis and Septic Shock,” last published in 2008. Design: A …

Objective: To provide an update to the original Surviving Sepsis Campaign clinical
management guidelines,“Surviving Sepsis Campaign Guidelines for Management of Severe …

Context Infection is a major cause of morbidity and mortality in intensive care units (ICUs)
worldwide. However, relatively little information is available about the global epidemiology …