User profiles for "author:H. Jacobs"

Heidi Jacobs

Massachusetts General Hospital & Maastricht University
Verified email at mgh.harvard.edu
Cited by 7613

[HTML][HTML] International consensus based review and recommendations for minimum reporting standards in research on transcutaneous vagus nerve stimulation …

AD Farmer, A Strzelczyk, A Finisguerra… - Frontiers in human …, 2021 - frontiersin.org
Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus
nerve stimulation (tVNS) across basic, translational and clinical research …

Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases

MJ Betts, E Kirilina, MCG Otaduy, D Ivanov… - Brain, 2019 - academic.oup.com
Pathological alterations to the locus coeruleus, the major source of noradrenaline in the
brain, are histologically evident in early stages of neurodegenerative diseases. Novel MRI …

Distribution, type, and origin of Parkin mutations: Review and case studies

…, P Vieregge, H Jacobs… - … : official journal of the …, 2004 - Wiley Online Library
Early‐onset Parkinson's disease (PD) has been associated with different mutations in the
Parkin gene (PARK2). To study distribution and type of Parkin mutations, we carried out a …

Ablation of metals by ultrashort laser pulses

S Nolte, C Momma, H Jacobs, A Tünnermann… - JOSA B, 1997 - opg.optica.org
Ablation of metal targets by Ti: sapphire laser radiation is studied. The ablation depth per
pulse is measured for laser pulse durations between 150 fs and 30 ps and fluences ranging …

[BOOK][B] Incidents in the Life of a Slave Girl

HA Jacobs - 2009 - books.google.com
This enlarged edition of the most significant and celebrated slave narrative completes the
Jacobs family saga, surely one of the most memorable in all of American history. John S …

Premature ageing in mice expressing defective mitochondrial DNA polymerase

A Trifunovic, A Wredenberg, M Falkenberg… - Nature, 2004 - nature.com
Point mutations and deletions of mitochondrial DNA (mtDNA) accumulate in a variety of
tissues during ageing in humans, monkeys and rodents. These mutations are unevenly …

[HTML][HTML] BET bromodomain inhibition as a therapeutic strategy to target c-Myc

JE Delmore, GC Issa, ME Lemieux, PB Rahl, J Shi… - Cell, 2011 - cell.com
MYC contributes to the pathogenesis of a majority of human cancers, yet strategies to
modulate the function of the c-Myc oncoprotein do not exist. Toward this objective, we have …

[BOOK][B] Interdisciplinary curriculum: Design and implementation.

HH Jacobs - 1989 - ERIC
This document describes a variety of curriculum integration options ranging from concurrent
teaching of related subjects to fusion of curriculum focus to residential study focusing on …

The Herschel-heterodyne instrument for the far-infrared (HIFI)

…, R Huisman, BD Jackson, H Jacobs… - Astronomy & …, 2010 - aanda.org
Aims. This paper describes the Heterodyne Instrument for the Far-Infrared (HIFI) that was
launched onboard ESA's Herschel Space Observatory in May 2009. Methods. The …

[PDF][PDF] Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages

EL Mills, B Kelly, A Logan, ASH Costa, M Varma… - Cell, 2016 - cell.com
Activated macrophages undergo metabolic reprogramming, which drives their pro-
inflammatory phenotype, but the mechanistic basis for this remains obscure. Here, we …