Tetrazolium salts have become some of the most widely used tools in cell biology for
measuring the metabolic activity of cells ranging from mammalian to microbial origin. With …

Glioblastoma is the most common malignant primary brain tumor. Overall, the prognosis for
patients with this disease is poor, with a median survival of< 2 years. There is a slight …

Progress in oncology drug development has been hampered by a lack of preclinical models
that reliably predict clinical activity of novel compounds in cancer patients. In an effort to …

Memory T cells induced by previous pathogens can shape susceptibility to, and the clinical
severity of, subsequent infections. Little is known about the presence in humans of pre …

Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the
elderly, with limited therapeutic options. Here we report on a study of> 12 million variants …

Background Enzalutamide, an androgen-receptor inhibitor, has been associated with
improved overall survival in men with castration-resistant prostate cancer. It is not known …

The MTT assay, which is widely used to measure cell proliferation and to screen for
anticancer drugs, is based on reduction of the tetrazolium salt, MTT (3-(4, 5-dimethylthiazol …

Machinery prognosis is the forecast of the remaining operational life, future condition, or
probability of reliable operation of an equipment based on the acquired condition monitoring …

Individuals with potential exposure to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) do not necessarily develop PCR or antibody positivity, suggesting that some …

Mitigating global infectious disease requires diagnostic tools that are sensitive, specific, and
rapidly field deployable. In this study, we demonstrate that the Cas13-based SHERLOCK …