Midazolam for intractable hiccup

J Pain Symptom Manage. 1996 Jul;12(1):59-61. doi: 10.1016/0885-3924(96)00051-6.

Abstract

We describe two terminally ill cancer patients severely distressed by intractable hiccup. Commonly recommended treatments were ineffective. Intravenous midazolam 5-10 mg rapidly relieved the hiccup. Maintenance treatment comprised midazolam 40-120 mg/24 hr by continuous subcutaneous infusion.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Hiccup / drug therapy*
  • Humans
  • Hypnotics and Sedatives / therapeutic use*
  • Kidney Neoplasms / complications
  • Kidney Neoplasms / pathology
  • Lung Neoplasms / secondary
  • Male
  • Midazolam / therapeutic use*
  • Middle Aged
  • Prostatic Neoplasms / complications
  • Terminal Care

Substances

  • Hypnotics and Sedatives
  • Midazolam