Abstract
We describe two terminally ill cancer patients severely distressed by intractable hiccup. Commonly recommended treatments were ineffective. Intravenous midazolam 5-10 mg rapidly relieved the hiccup. Maintenance treatment comprised midazolam 40-120 mg/24 hr by continuous subcutaneous infusion.
MeSH terms
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Aged
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Hiccup / drug therapy*
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Humans
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Hypnotics and Sedatives / therapeutic use*
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Kidney Neoplasms / complications
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Kidney Neoplasms / pathology
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Lung Neoplasms / secondary
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Male
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Midazolam / therapeutic use*
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Middle Aged
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Prostatic Neoplasms / complications
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Terminal Care
Substances
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Hypnotics and Sedatives
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Midazolam