Patient self-report of symptoms and physical functioning
| N=1698 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Variables | Mean | SD | Missing | N 0–3 | % 0–3 | N 4–6 | % 4–6 | N 7–10 | % 7–10 |
| Pain* | 2.1 | 2.3 | 14 | 1246 | (74) | 308 | (18) | 141 | (8) |
| Tiredness* | 4.3 | 3.0 | 13 | 654 | (41) | 541 | (32) | 450 | (27) |
| Nausea* | 1.0 | 2.1 | 21 | 1471 | (88) | 138 | (8) | 68 | (4) |
| Depression* | 2.5 | 2.9 | 17 | 1144 | (68) | 318 | (19) | 219 | (13) |
| Anxiety* | 2.3 | 2.8 | 18 | 1183 | (70) | 315 | (19) | 192 | (11) |
| Drowsiness* | 3.1 | 2.9 | 31 | 994 | (60) | 396 | (23) | 277 | (16) |
| Appetite* | 3.0 | 3.2 | 23 | 1322 | (78) | 240 | (14) | 128 | (8) |
| Well-being* | 3.6 | 2.7 | 35 | 837 | (50) | 552 | (33) | 274 | (17) |
| Shortness of breath* | 1.8 | 2.5 | 14 | 1320 | (78) | 238 | (14) | 26 | (8) |
| Pain intensity, average past 24 hours† | 3.2 | 2.7 | 9 | 991 | (59) | 449 | (26) | 249 | (15) |
| Pain intensity, worst, past 24 hours† | 4.0 | 3.3 | 21 | 796 | (47) | 418 | (25) | 463 | (27) |
| Physical functioning‡ | 64.3 | 29.2 | 14 | ||||||
| N yes | % yes | ||||||||
| PHQ9 depression§ | 339 | (20) | 28 | ||||||
| Anhedonia | 553 | (32) | 33 | ||||||
| Depressed mood | 437 | (26) | 30 | ||||||
| Neuropathic pain¶ | 560 | (34) | 65 | ||||||
| Breakthrough pain last 24 hours** | 608 | (37) | 44 | ||||||
*ESAS-r: 0–10 scale, higher score implies higher symptom intensity/poorer well-being, ‘right now’.19
†BPI: 0–10 scale, higher score implies higher pain intensity.15
‡QLQ-C15-PAL: 0–100 scale, higher score implies better functioning.20
§PHQ9: ‘yes’ indicates a score of 2 or 3 on the 0–3 scale assessing the frequency at which people have been bothered by anhedonia (little interest or pleasure in doing things) and depressed mood during the past 2 weeks: 2=‘more than half the days’ and 3=‘nearly every day’.18
¶‘Does the skin in the painful area feel different from normal, more numb or more sensitive?’: yes/no, adapted from PainDetect.16
**‘Have you had flare-ups of breakthrough pain in the last 24 hours?’: yes/no, adapted from the Alberta Breakthrough Pain Assessment Tool.17