ANTI-TUMOUR TREATMENTShort- and long-term effects of acute myeloid leukemia on patient health-related quality of life
Section snippets
Objectives
Increasing attention is being devoted to quantifying the health-related quality of life (HRQL) impact of different types of cancer and their therapeutic alternatives. Acute myeloid leukemia (AML) is treated aggressively with such therapies as chemotherapy and bone marrow transplantation (BMT), which are thought to significantly affect patient HRQL. Therefore, the goal of this study was to systematically assess and summarize what is known about the HRQL impact on patients of AML and its
Methods
This review process began with a systematic, electronically assisted search of English-language articles published by the international scientific community between 1990 and 2002. To maximize the sensitivity of the initial search, thereby promoting rapid and efficient identification of all potentially relevant articles, the initial search was conducted upon the MEDLINE database using the following broad Medical Subject Headings [MESH] and “text only” search terms: “acute myeloid leukemia” or
Results
The survey identified 21 articles that warranted review, 19 of which have been published in the past decade, since 1993.[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21] The majority of the 21 have been published since 1997 (inclusive), although the oldest article was published in 1989.10
Conclusion
AML and the intensive treatment (e.g., chemotherapy, BMT, SCT) required to cure a patient with AML have a substantial negative impact on patient HRQL that has been measured by several different generic, cancer-specific and leukemia-specific instruments. The most negative HRQL burden is apparent after the diagnosis of the disease and during the course of the therapy. However, long-term survivors appear to recover almost completely as evidenced by scores in physical, psychological and emotional
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2018, PsychoneuroendocrinologyDifferences in the economic valuation and determining factors of informal care over time: the case of blood cancer
2018, Gaceta SanitariaCitation Excerpt :Cancer is a disease that greatly changes the life of the patients throughout their treatment. Caregiver assistance in daily activities not only limited to personal care or household care, but also as psychological support, can be crucial for many patients.1–5 In this regard, the informal caregiver has played an essential role throughout history being recognized by the World Health Organization.6